Suffering from noise issues in my setup I had traced down to a combination of an Artec Power Brick introducing extreme amounts of common mode noise, and a long cable run towards my amplifier bleeding that noise into the signal due to imperfect conductance across the shield, I sought to address this by getting shorter cables and a power supply that may inject less noise into my signal chain. The ISO-1AC Pro Modular however suffers from the same ills as many a non-isolated switch-mode pedal power supply, and while very marginally less noisy across the same cable run, it has proven very temperamental, introducing a high pitched whine whenever I interact with the guitar with a mere three analog pedals powered, and not even switched on, running into my amplifier, even when I shorten the final cable run to a mere 0.9m to eliminate most of the remaining common mode noise bleed. The sheer noisiness of the power proves to be a problem when powering anything floating as well, a tuner connected one-way to an isolated line out / fx send injects so much hum into the amplifier you can forget about playing anything. Of course, this will go for any low quality switch-mode power supply, but that particular use-case is even more doomed than with a daisy-chain or negative-linked brick, since in those scenarios at least the device is capable of sharing a ground and bleeding off most of the power supply noise. The isolation of the outputs from each other does the heavy lifting in keeping this power supply from letting pedals ruin each other's day, but if you're in a situation where the pedals aren't disagreeing with each other, and your high-gain amplifier simply disagrees with being connected to a high-noise switch-mode power supply of any kind, then this power supply seems to introduce more problems than it solves.